Translations:Advanced Field Epi:Manual 1 - Disease Investigation/294/en
| style="background-color:#ffffff;border:0.5pt solid #00000a;padding-top:0cm;padding-bottom:0cm;padding-left:0.199cm;padding-right:0.191cm;"| * Exposed/unexposed proportions cannot be estimated
- Large sample sizes, particularly for rare diseases
- Can only investigate small number of potential risk factors at any one time
- Long duration of follow-up
- Relatively expensive and time-consuming
- Loss of individuals to follow-up
- May be difficult to control potential confounders