Translations:Advanced Field Epi:Manual 1 - Disease Investigation/438/en

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{{example|In 1994, an incident occurred in Queensland where a previously unidentified virus (since characterised as Hendra virus) was responsible for the death of 14 horses and one human (with a second affected human subsequently recovering), associated with a single racehorse stable ([#1 Baldock et al., 1996]). During the investigation it became rapidly apparent that this was a previously unidentified disease, and that the aetiology was unknown. However, even before the causal virus was identified, it was possible to determine that it was probably infectious in nature; was most likely to be directly transmitted; was not highly contagious (either among horses or humans); and that it probably originated from an, as then, unidentified wildlife reservoir ([#2 Baldock et al., 1995]). Just on one year after the Hendra outbreak, flying foxes (fruit bats) were identified as the presumptive natural host of the virus, with about 14% of flying foxes sampled being seropositive ([#1 Baldock et al., 1996]). The virus was subsequently isolated from uterine fluids of a flying fox ([#12 Halpin et al., 1996]). Flying foxes were known to feed in trees in a spelling paddock associated with the stable and in which the index case was grazing prior to becoming sick. The specific mechanism of transmission among bats and from bats to horses is still not known.