Wiki Sumber Informasi iSIKHNAS

• If the objective is to confirm a likely diagnosis (the "rule-in" situation), then choose a test which has high specificity (~>95%) and at least moderate sensitivity (~>75%). If a positive result is returned, then it is highly likely the individual has the disease in question (PPV's are high for tests with high specificity). If a negative result is returned, then further diagnostic work up is required.
• If the objective is to confirm that an individual is free from a particular disease (the "rule-out" situation), then choose a test with high sensitivity (~>95%) and at least moderate specificity (~>75%). If a negative result is returned, then it is highly likely the individual is free from the disease in question. If a positive result is returned, then further testing is required with more specific tests to ascertain whether or not the result was a false positive result or not.