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 r Inggris (en)* The tests are independent, conditional on disease status (the sensitivity [specificity] of one test is the same, regardless of the result of the other test, as discussed in more detail in the section on series and parallel interpretation of tests);
* Test sensitivity and specificity are constant across populations;
* The tests are compared in two or more populations with different prevalence between populations; and 
* There are at least as many populations as there are tests being evaluated.