Translations:Advanced Field Epi:Manual 1 - Disease Investigation/316/en

Sometimes controls are selected in a process that involves matching on a defined attribute with each case. For example, a 2-year old cow with diarrhoea (case) may be matched with a 2-year old cow without diarrhoea (matched control). Matching is usually used to control for some form of confounding between the factor being used for matching (age) and the association between some other possible causal factors and the disease of interest. When a factor is matched it cannot be analysed for an association with disease. Matching is a complex topic and should not be attempted without advice from a veterinary epidemiologist.