Translations:Advanced Field Epi:Manual 2 - Diagnostic Tests/235/en

For example, this approach was used to estimate sensitivity and specificity for ELISA for Toxoplasma gondii infection in Dutch sheep ([#14 Opsteegh et al., 2010]). ELISA results from 1,179 serum samples collected from sheep at slaughterhouses in the Netherlands were log transformed and normal distributions fitted to the infected and uninfected components. The resulting theoretical distributions allowed determination of a suitable cut-point with estimated sensitivity of 97.8% and specificity of 96.4%.